The documentary focuses on criticizing atheism, as well as science, for its perceived similarities to religion, as well as arrogance and intolerance. The program includes interviews with a number of prominent scientists, including atheists Richard Dawkins and Peter Atkins and Anglican priest John Polkinghorne. It also includes an interview with Ellen Johnson, the president of American Atheists. Rod Liddle begins the documentary by surveying common criticisms of religion, and particularly antireligious arguments based on the prevalence of religious violence. He argues that the “very stupid human craving for certainty and justification”, not religion, is to blame for this violence, and that atheism is becoming just as dogmatic as religion.